J.P Jaffrèzou: search on Z-Library

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1

Signalling sphingomyelinases: which, where, how and why?

Thierry Levade, Jean-Pierre Jaffrézou

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

1999

Language:

english

File:

PDF, 209 KB

english, 1999

2

Sensitivity of fresh leukemic cells to T101 ricin a-chain immunotoxin: A comparative study between Fab fragment and whole Ig conjugates

M. Chiron, J.M. Derocq, E. Kuhlein, F. Roubinet, C. Demur, H. Grandjean, F. Huguet, J.P. Jaffrezou, F. Jansen, G. Laurent

Journal:

Leukemia Research

Year:

1989

Language:

english

File:

PDF, 769 KB

english, 1989

3

Verapamil decreases P-glycoprotein expression in multidrug-resistant human leukemic cell lines

Catherine Muller, Jean-Denis Bailly, Françoise Goubin, Judith Laredo, Jean-Pierre Jaffrézou, Christine Bordier, Guy Laurent

Journal:

International Journal of Cancer

Year:

1994

Language:

english

File:

PDF, 1.04 MB

english, 1994

4

Phosphatidylcholine-derived phosphatidic acid and diacylglycerol are involved in the signaling pathways activated by docetaxel

Nicolas Maestre, Christine Bezombes, Isabelle Plo, Thierry Levade, François Lavelle, Guy Laurent, Jean-Pierre Jaffrézou

Journal:

Journal of Experimental Therapeutics and Oncology

Year:

2003

Language:

english

File:

PDF, 462 KB

english, 2003

5

Implication of Radical Oxygen Species in Ceramide Generation, c-Jun N-Terminal Kinase Activation and Apoptosis Induced by Daunorubicin

Mas, Véronique Mansat-De, Bezombes, Christine, Quillet-Mary, Anne, Bettaïeb, Ali, D’orgeix, Aurélie De Thonel, Laurent, Guy, Jaffrézou, Jean-Pierre

Journal:

Molecular Pharmacology

Year:

1999

File:

PDF, 373 KB

1999

6

Drug Evaluation: Oncologic, Endocrine & Metabolic: Docetaxel (Taxotere®): current status and clinical prospects

Jaffrézou, Jean-Pierre, Laurent, Guy

Journal:

Expert Opinion on Investigational Drugs

Year:

1995

File:

PDF, 1.27 MB

1995

7

Effect of the protein kinase C inhibitor staurosporine on chemosensitivity to daunorubicin of normal and leukemic fresh myeloid cells

Laredo, J, Huynh, A, Muller, C, Jaffrezou, JP, Bailly, JD, Cassar, G, Laurent, G, Demur, C

Journal:

Year:

1994

File:

PDF, 2.18 MB

1994

8

Opposite effects of tumor necrosis factor alpha on the sphingomyelin- ceramide pathway in two myeloid leukemia cell lines: role of transverse sphingomyelin distribution in the plasma membrane

Bettaieb, A, Record, M, Come, MG, Bras, AC, Chap, H, Laurent, G, Jaffrezou, JP

Journal:

Year:

1996

File:

PDF, 2.34 MB

1996

9

Drug Evaluation: Oncologic, Endocrine & Metabolic: Docetaxel (Taxotere®): current status and clinical prospects

Jaffrézou, Jean-Pierre, Laurent, Guy

Journal:

Expert Opinion on Investigational Drugs

Year:

1995

Language:

english

File:

PDF, 1.27 MB

english, 1995

10

Mutation Rates and Mechanisms of Resistance to Etoposide Determined From Flucattion Analysis

Jaffrezou, J.-P., Chen, G., Duran, G. E., Kuhl, J.-S., Sikic, B. I.

Journal:

JNCI Journal of the National Cancer Institute

Year:

1994

Language:

english

File:

PDF, 4.19 MB

english, 1994

11

Sphingolipids as modulators of cancer cell death: Potential therapeutic targets

Bruno Ségui, Nathalie Andrieu-Abadie, Jean-Pierre Jaffrézou, Hervé Benoist, Thierry Levade

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2006

Language:

english

File:

PDF, 408 KB

english, 2006

12

Phosphatidylcholine-specific phospholipase C and phospholipase D are respectively implicated in mitogen-activated protein kinase and nuclear factor κB activation in tumour-necrosis-factor-α-treated immature acute-myeloid-leukaemia cells

PLO, Isabelle, LAUTIER, Dominique, LEVADE, Thierry, SEKOURI, Hadef, JAFFRÉZOU, JeanPierre, LAURENT, Guy, BETTAÏEB, Ali

Journal:

Biochemical Journal

Year:

2000

Language:

english

File:

PDF, 222 KB

english, 2000

13

Molecular Mechanisms of Apoptosis Induced by an Immunomodulating Peptide on Human Monocytes

Juan A. Osés-Prieto, Natalia López-Moratalla, Esteban Santiago, Jean P. Jaffrézou, Maria J. López-Zabalza

Journal:

Archives of Biochemistry and Biophysics

Year:

2000

Language:

english

File:

PDF, 258 KB

english, 2000

14

Implication of Mitochondrial Hydrogen Peroxide Generation in Ceramide-induced Apoptosis

Quillet-Mary, A., Jaffrezou, J.-P., Mansat, V., Bordier, C., Naval, J., Laurent, G.

Journal:

Journal of Biological Chemistry

Year:

1997

Language:

english

File:

PDF, 927 KB

english, 1997

15

Cyclosporin A and cyclosporin SDZ PSC 833 enhance anti-CD5 ricin A- chain immunotoxins in human leukemic T cells

Jaffrezou, JP, Sikic, BI, Laurent, G

Journal:

Year:

1994

File:

PDF, 1.43 MB

1994

16

Effects of an anti HLA-DR immunotoxin on leukaemia cells and hematopoietic progenitors

C. Demur, J.M. Derocq, P. Poncelet, M. Chiron, F. Roubinet, J.P. Jaffrezou, C. Bordier, G. Laurent

Journal:

Leukemia Research

Year:

1989

Language:

english

File:

PDF, 652 KB

english, 1989

17

Low Temperatures and Hypertonicity Do Not Block Cytokine-induced Stimulation of the Sphingomyelin Pathway but Inhibit Nuclear Factor- B Activation

Andrieu, N., Salvayre, R., Jaffrezou, J.-P., Levade, T.

Journal:

Journal of Biological Chemistry

Year:

1995

Language:

english

File:

PDF, 210 KB

english, 1995

18

The intriguing link between modulation of both multidrug resistance and ligand-toxin conjugate cytotoxicity

Jean-Pierre Jaffrézou, Guy Laurent

Journal:

Year:

1993

Language:

english

File:

PDF, 787 KB

english, 1993

19

Sensitivity of fresh acute myeloid leukemia cells to etoposide: relationship with cell growth characteristics and DNA single-strand breaks

Chiron, M, Demur, C, Pierson, V, Jaffrezou, JP, Muller, C, Saivin, S, Bordier, C, Bousquet, C, Dastugue, N, Laurent, G

Journal:

Year:

1992

File:

PDF, 932 KB

1992

20

Sphingomyelin-degrading pathways in human cells: Role in cell signalling

Thierry Levade, Nathalie Andrieu-Abadie, Bruno Ségui, Nathalie Augé, Martine Chatelut, Jean-Pierre Jaffrézou, Robert Salvayre

Journal:

Chemistry and Physics of Lipids

Year:

1999

Language:

english

File:

PDF, 190 KB

english, 1999

21

Quantitative analysis of CD5 antigen modulation by 12-O-tetradecanoylphorbol-13-acetate in T-lymphoblastic leukemia cells: Individual response patterns and their relationships with both maturation and protein kinase C content

M. Chiron, J.M. Darbon, F. Roubinet, G. Cassar, J.P. Jaffrezou, C. Bordier, G. Laurent

Journal:

Cellular Immunology

Year:

1990

Language:

english

File:

PDF, 890 KB

english, 1990

22

p38 MAPK mediates the regulation of α1(I) procollagen mRNA levels by TNF-α and TGF-β in a cell line of rat hepatic stellate cells

M Varela-Rey, C Montiel-Duarte, J.A Osés-Prieto, M.J López-Zabalza, J.P Jaffrèzou, M Rojkind, M.J Iraburu

Journal:

Year:

2002

Language:

english

File:

PDF, 267 KB

english, 2002

23

L-carnitine prevents doxorubicin-induced apoptosis of cardiac myocytes: role of inhibition of ceramide generation

ANDRIEU-ABADIE, NATHALIE, JAFFRÉZOU, JEAN-PIERRE, HATEM, STÉPHANE, LAURENT, GUY, LEVADE, THIERRY, MERCADIER, JEAN-JACQUES

Journal:

The FASEB Journal

Year:

1999

Language:

english

File:

PDF, 335 KB

english, 1999

24

Lack of ceramide generation in TF-1 human myeloid leukemic cells resistant to ionizing radiation

Bruno, Alain P, Laurent, Guy, Averbeck, Dietrich, Demur, Cécile, Bonnet, Jacques, Bettaïeb, Ali, Levade, Thierry, Jaffrézou, Jean-Pierre

Journal:

Cell Death & Differentiation

Year:

1998

Language:

english

File:

PDF, 381 KB

english, 1998

25

Stress-induced apoptosis is not mediated by endolysosomal ceramide

SÉGUI, BRUNO, BEZOMBES, CHRISTINE, URO-COSTE, EMMANUELLE, MEDIN, JEFFREY A., ANDRIEU-ABADIE, NATHALIE, AUGÉ, NATHALIE, BROUCHET, ANNE, LAURENT, GUY, SALVAYRE, ROBERT, JAFFRÉZOU, JEAN-PIERRE, LEVADE, T

Journal:

The FASEB Journal

Year:

2000

Language:

english

File:

PDF, 373 KB

english, 2000

26

Con A activates an Akt/PKB dependent survival mechanism to modulate TCR induced cell death in double positive thymocytes

Judit Pongracz, Sonia Parnell, Graham Anderson, Jean-Pierre Jaffrézou, Eric Jenkinson

Journal:

Molecular Immunology

Year:

2003

Language:

english

File:

PDF, 540 KB

english, 2003

27

CD40 Signals Apoptosis through FAN-regulated Activation of the Sphingomyelin-Ceramide Pathway

Segui, B., Andrieu-Abadie, N., Adam-Klages, S., Meilhac, O., Kreder, D., Garcia, V., Bruno, A. P., Jaffrezou, J.-P., Salvayre, R., Kronke, M., Levade, T.

Journal:

Journal of Biological Chemistry

Year:

1999

Language:

english

File:

PDF, 1.05 MB

english, 1999

28

Phosphatidylcholine-specific phospholipase C and phospholipase D are respectively implicated in mitogen-activated protein kinase and nuclear factor κB activation in tumour-necrosis-factor-α-treated immature acute-myeloid-leukaemia cells

PLO, Isabelle, LAUTIER, Dominique, LEVADE, Thierry, SEKOURI, Hadef, JAFFRÉZOU, Jean Pierre, LAURENT, Guy, BETTAÏEB, Ali

Journal:

Biochemical Journal

Year:

2000

Language:

english

File:

PDF, 222 KB

english, 2000

29

Activation of a nuclear sphingomyelinase in radiation-induced apoptosis

JAFFREZOU, J.-P.

Journal:

The FASEB Journal

Year:

2001

Language:

english

File:

PDF, 583 KB

english, 2001

30

The Acid Sphingomyelinase Inhibitor SR33557 Counteracts TNF-α-Mediated Potentiation of IL-1β-Induced NF-κB Activation in the Insulin-Producing Cell Line RINm5F

Saldeen, Johan, Jaffrezou, Jean-Pierre, Welsh, Nils

Journal:

Year:

2000

Language:

english

File:

PDF, 1.18 MB

english, 2000

31

UV-C Light Induces Raft-associated Acid Sphingomyelinase and JNK Activation and Translocation Independently on a Nuclear Signal

Charruyer, A., Grazide, S., Bezombes, C., Muller, S., Laurent, G., Jaffrezou, J.-P.

Journal:

Journal of Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 1017 KB

english, 2005

32

Multidrug-resistant Human Sarcoma Cells with a Mutant P-Glycoprotein, Altered Phenotype, and Resistance to Cyclosporins

Chen, G., Duran, G. E., Steger, K. A., Lacayo, N. J., Jaffrezou, J.-P., Dumontet, C., Sikic, B. I.

Journal:

Journal of Biological Chemistry

Year:

1997

Language:

english

File:

PDF, 980 KB

english, 1997

33

Sphingomyelin content conditions insertion of daunorubicin within phosphatidylcholine monolayers

Marie-France Lecompte, Guy Laurent, Jean-Pierre Jaffrézou

Journal:

Year:

2002

Language:

english

File:

PDF, 106 KB

english, 2002

34

DNase I susceptibility of bent DNA and its alteration by ditercalinium and distamycin

Mendoza, Roberto, Markovits, Judith, Jaffrezou, Jean Pierre, Muzard, Gabriel, Le Pecq, Jean Bernard

Journal:

Year:

1990

Language:

english

File:

PDF, 1.55 MB

english, 1990

35

Cytoprotective Effect of Glucosylceramide Synthase Inhibition against Daunorubicin-induced Apoptosis in Human Leukemic Cell Lines

Grazide, S., Terrisse, A.-D., Lerouge, S., Laurent, G., Jaffrezou, J.-P.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 742 KB

english, 2004

36

Antitumor Agent-Induced Apoptosis in Myeloid Leukemia Cells: A Controlled Suicide

Jaffrézou, Jean-Pierre, Bettaïeb, Ali, Levade, Thierry, Laurent, Guy

Journal:

Leukemia and Lymphoma

Year:

1998

Language:

english

File:

PDF, 1.18 MB

english, 1998

37

Genotypical instability in undifferentiated cells: precursors for environmental adaptability?

Bruno, Alain P, Laurent, Guy, Demur, Cécile, Jaffrezou, Jean-Pierre

Journal:

Cell Death & Differentiation

Year:

2001

Language:

english

File:

PDF, 53 KB

english, 2001

38

Daunorubicin- and Ara-C-induced interphasic apoptosis of human Type II leukemia cells is caspase-8-independent

Anne-Dominique Terrisse, Christine Bezombes, Sandra Lerouge, Guy Laurent, Jean-Pierre Jaffrézou

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2002

Language:

english

File:

PDF, 268 KB

english, 2002

39

Daunorubicin-induced apoptosis: triggering of ceramide generation through sphingomyelin hydrolysis.

Jaffrézou, J. P., Levade, T., Bettaïeb, A., Andrieu, N., Bezombes, C., Maestre, N., Vermeersch, S., Rousse, A., Laurent, G.

Journal:

The EMBO Journal

Year:

1996

Language:

english

File:

PDF, 1.67 MB

english, 1996

40

PKCζ protects against UV-C-induced apoptosis by inhibiting acid sphingomyelinase-dependent ceramide production

Charruyer, Alexandra, Jean, Christine, Colomba, Audrey, Jaffrézou, Jean-Pierre, Quillet-Mary, Anne, Laurent, Guy, Bezombes, Christine

Journal:

Biochemical Journal

Year:

2007

Language:

english

File:

PDF, 304 KB

english, 2007

41

Induction and increase of HLA-DR antigen expression by immune interferon on ML-3 cell line enhances the anti-HLA-DR immunotoxin activity

M. CHIRON, J. P. JAFFREZOU, P. CARAYON, C. BORDIER, F. ROUBINET, C. XAVIER, M. BRANDELY, G. LAURENT

Journal:

Clinical & Experimental Immunology

Year:

1990

Language:

english

File:

PDF, 2.88 MB

english, 1990

42

Potential Role for Ceramide in Mitogen-activated Protein Kinase Activation and Proliferation of Vascular Smooth Muscle Cells Induced by Oxidized Low Density Lipoprotein

Auge, N., Escargueil-Blanc, I., Lajoie-Mazenc, I., Suc, I., Andrieu-Abadie, N., Pieraggi, M.-T., Chatelut, M., Thiers, J.-C., Jaffrezou, J.-P., Laurent, G., Levade, T., Negre-Salvayre, A., Salvayre, R

Journal:

Journal of Biological Chemistry

Year:

1998

Language:

english

File:

PDF, 679 KB

english, 1998

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